Cancer isn’t one disease, but many with different characteristics and treatments. Because they’re not as widely studied, rarer cancers can have higher mortality rates. This is the case with CNS-PNETs, certain types of brain cancer in children. However, scientists recently developed a very similar type of cancer in zebrafish – shown here, with the fuchsia area marking the tumour. These can be used to test potential treatments, and researchers have already found one interesting candidate. A compound that inhibits a gene called MEK – already being looked at as a potential treatment for other cancers – successfully treated the cancer in a majority of the fish. An exciting subject for future research, this model could soon be used to test cells from the tumours of individual patients, helping develop treatments that are personalised to work best for them.
Written by Esther Redhouse White
BPoD stands for Biomedical Picture of the Day. Managed by the MRC Clinical Sciences Centre the website aims to engage everyone, young and old, in the wonders of biomedicine. Images are kindly provided for inclusion on this website through the generosity of scientists across the globe.