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Sound the Alarm
02 December 2015

Sound the Alarm

The inner ear is a delicate structure, generating the sensation of sound thanks to fragile hair cells, detecting the pressure of sound waves. Sensory neurons, known as type I afferents, then transmit the signals from the hair cells to the brain. However, very loud noises can destroy hair cells, permanently degrading our sense of hearing. Type II afferent neurons are relatively insensitive to sound, but respond when outer hair cells, those closest to danger, are damaged; like pain receptors in the skin, their role is to warn the brain, so that we can protect ourselves before more cells are lost. In the rat’s inner ear shown, a type II afferent stretches from the outer hair cells to the brain, where its cell body forms a dark spot near the centre of the picture. Studying how these neurons operate could provide new insights into hyperacusis, a painful hyper-sensitivity to noise.

Written by Emmanuelle Briolat

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BPoD stands for Biomedical Picture of the Day. Managed by the MRC Laboratory of Medical Sciences until Jul 2023, it is now run independently by a dedicated team of scientists and writers. The website aims to engage everyone, young and old, in the wonders of biology, and its influence on medicine. The ever-growing archive of more than 4000 research images documents over a decade of progress. Explore the collection and see what you discover. Images are kindly provided for inclusion on this website through the generosity of scientists across the globe.

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