Investigating what the diagnostic and therapeutic intervention transcranial magnetic stimulation actually does to the brain
Have you ever got lost trying to navigate a dense city with a hopelessly vague map? Sometimes that’s what it’s like trying to unpick the complexity of the human brain. For example, transcranial magnetic stimulation is a treatment used for various mental illnesses such as depression and Alzheimer’s, but how exactly it works is a mystery. To investigate what the procedure – which involves firing small electric currents at regions of the brain – actually does, researchers looked at brain ‘orientation maps’ before and after the treatment (pictured – the left of each pair is before the procedure, right after). The colours reflect specific neurons’ orientations in response to visual cues, many of which have changed after the procedure. And visual ‘training’ after the treatment contributed to these updated neural ‘maps’, suggesting that post-treatment behaviour could help redirect misguided brain connections. A promising addition to our incomplete map of the brain’s vast complexity.
BPoD stands for Biomedical Picture of the Day. Managed by the MRC London Institute of Medical Sciences the website aims to engage everyone, young and old, in the wonders of biomedicine. Images are kindly provided for inclusion on this website through the generosity of scientists across the globe.
BPoD is also available in Catalan at www.bpod.cat with translations by the University of Valencia.