Medical Research Council - London Institute of Medical Sciences

Now in our 12th year of bringing you beautiful imagery from biomedical science every day

Redundant Proteins
23 March 2012

Redundant Proteins

Cilia, hair-like protrusions, are common throughout our body. They can move cells, waft fluid and sense the surroundings. Pictured here are cilia (stained green) that sense head movement in zebrafish ear cells. The proteins that make up these ‘hairs’ must be exported from the cell (surface stained red) by proteins called kinesins. Kinesins constitute a large protein family with various important developmental roles. On the left a normal cell is visualised using a confocal microscope, with fully developed healthy cilia. When kinesin protein Kif3b is knocked-out (right) they’re still healthy. Cilia defects were found in these cells only when Kif3c was knocked-out. On the other hand, to grow a different type of cilia in zebrafish retina, kinesin type Kif3b is needed from day one. Discovering kinesin diversity helps in understanding how human cells develop and function.

Written by Rebecca Hill

Search The Archive

Submit An Image

What is BPoD?

BPoD stands for Biomedical Picture of the Day. Managed by the MRC London Institute of Medical Sciences the website aims to engage everyone, young and old, in the wonders of biomedicine. Images are kindly provided for inclusion on this website through the generosity of scientists across the globe.

Read More

BPoD is also available in Catalan at with translations by the University of Valencia.